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Rev. méd. Chile ; 144(7): 931-936, jul. 2016. ilus, tab
Article in Spanish | LILACS | ID: lil-794007

ABSTRACT

We report a 41-year-old man with HIV and a chronic obstructive pulmonary disease, treated for seven months with Fluticasone/Salmeterol and antiretroviral therapy (Lamivudine, Tenofovir, Atazanavir and Ritonavir). While using these medications, the patients developed a Cushing syndrome in a period of five months. After performing laboratory and imaging tests, it was concluded that the most probable cause of the syndrome was the interaction of inhaled steroids with Ritonavir. After discontinuing these medications the syndrome reverted in a period of 8 months.


Subject(s)
Humans , Male , Adult , Bronchodilator Agents/adverse effects , HIV Infections/drug therapy , HIV Protease Inhibitors/adverse effects , Cushing Syndrome/chemically induced , Salmeterol Xinafoate/adverse effects , Fluticasone/adverse effects , Nebulizers and Vaporizers , Bronchodilator Agents/therapeutic use , HIV Protease Inhibitors/therapeutic use , Cushing Syndrome/diagnosis , Drug Interactions , Salmeterol Xinafoate/therapeutic use , Fluticasone/therapeutic use
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